Tuberculous meningitis is the most common presentation of intracranial tuberculosis, and usually refers to infection of the leptomeninges. Uncommonly. Published online: January 07, Issue release date: Number of Print Pages: Number of Figures: 0. Number of Tables: 0. ISSN: (Print). Tuberculous meningitis (TBM) develops in 2 steps. Mycobacterium tuberculosis bacilli enter the host by droplet inhalation.

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Tuberculous meningitis is the most common presentation of intracranial tuberculosisand usually refers to infection of the leptomeninges.

The tuberxulosa of this article pertains to leptomeningeal tuberculosis, which involves the arachnoid mater and pia mater. In low prevalence areas it is more frequently encountered in adolescents and adults.

Most common clinical manifestations are fever, headache, vomiting and neck stiffness. Seizures, focal neurological deficits, stupor and coma may be seen in late stages.


CSF analysis reveals lymphocytosis, increased protein level and decreased glucose levels. Tuberculous meningitis is caused by Mycobacterium tuberculosis. The infection spreads hematogenously from a distant focal point, usually pulmonary tuberculosis and lodges immediately deep to the pia forming Rich foci.

These can rupture into the subarachnoid space, forming an exudate. This purulent material is primarily located in vicinity of basal cisterns: From here, infection spreads to interpeduncular cisternsaround optic chiasm and to pontomesencephalic, ambient and suprasellar cisterns. Although the exudate can reach the Sylvian fissures it uncommonly extends over the cerebral convexities 3.

Tuberculous meningitis

Choroid plexitis may also be a late manifestation as is mass-like regions of caesous necrosis within this exudate. Anti-tuberculosis regimen is started after confirmation of diagnosis. tuberdulosa

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Check for errors and leptomenigitis again. Thank you for updating your details. Log in Sign up. Articles Cases Courses Quiz. About Blog Go ad-free. MR imaging and angiography in tuberculous meningitis. MR imaging and leptomeningitls of central nervous system infection. Read it at Google Books – Find it at Amazon 4. Read it at Google Books – Find it at Amazon 5. Kornienko VN, Pronin I. Read it at Google Books – Find it at Amazon.

Tuberculous meningitis – Wikipedia

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